Firstly, it is important to know the differences between in Vitro Fertilization (IVF) and Artificial Insemination (AI), because they are 2 concepts that are very often mishandled.

In general, from artificial insemination with a partner's semen we cannot expect a probability of pregnancy greater than 12-15% per cycle. This must make it very clear to us that treatments carried out through insemination cannot be prolonged in time - a maximum of 3 cycles is what is currently indicated. If pregnancy has not been achieved in 3 cycles, it does not make much sense to continue down this path.

IVF Cost in Pakistan, in which what is achieved is to achieve the embryo inside the laboratory -in vitro-, and in artificial insemination (AI) the embryo is gestated inside the female genitals, that is, it is a live fertilization. Artificial insemination has historically been one of the most used treatments due to its relative simplicity, but it is hampered by poor results.

ARTIFICIAL INSEMINATION

• It involves the introduction of semen, previously selected, into the uterus of the woman who has been prepared by stimulating ovulation.
• Fertilization (union of egg and sperm) happens “in vivo”, inside the woman, specifically in the tube.
• It is a simpler technique since it does not require the extraction of the eggs.
• Ovarian stimulation should be minimal to avoid the risk of multiple pregnancy. The growth of more than 2 or 3 follicles should make us consider cancellation
• It is more economical. Considering the cost per treatment.
• The chances of success are lower. About 15% per attempt considering couples with a good prognosis.
• It does not provide real possibilities of success in cases of tubal obstruction or severe male factors.
• It offers very poor results when the sterility period is greater than 3 years, it is a moderate male factor or the woman suffers from endometriosis.
• Provides little information during treatment.
• It is an option to consider in couples with a good prognosis (young, short search time, without significant seminal alterations and without alterations in the tubes or endometriosis).

IN VITRO FERTILIZATION

• It consists of the extraction of the woman's eggs to be fertilized in the laboratory and the subsequent introduction of the embryos obtained inside her uterus.
• Fertilization happens “in vitro”, outside the woman, in the laboratory.
• It is a more complex technique, requiring a surgical procedure to obtain the eggs and fertilize them in the laboratory.
• Ovarian stimulation aims to obtain an adequate number of eggs, which we can estimate between 6 and 15.
• The economic effort is higher although it is more economical if we consider the cost per child born.
• It is the treatment with the greatest chance of success per attempt. According to Best IVF Center in Pakistan.In certain cases, the probability of pregnancy reaches 60%
• The chances of success, except in extreme cases, are independent of the alterations of the tubes and the severity of the male factor.
• It can be considered the first option in couples with prolonged infertility, moderate male factors and women with endometriosis.
• Valuable information is obtained during treatment as important factors such as ovarian response to stimulation, oocyte quality, fertilization and embryo evolution are evaluated.
• The space that intrauterine insemination currently occupies is for those low-complexity treatments, because today in vitro fertilization will give us a higher performance than artificial insemination.

Conclusion

Unlike what happened approximately 25-30 years ago where there were no major differences in terms of pregnancy success comparing inseminations in several cycles or in vitro fertilization, currently this separation has become greater every day and today in vitro fertilization It will have a much better chance of success than several insemination cycles. But not only that; Furthermore, in insemination we have a risk, the risk of multiple pregnancy.

In in vitro fertilization we can perfectly control the number of embryos we transfer, while in insemination we cannot predict, it is impossible to ensure 100% that the ovarian response does not give rise to multiple ovulation, as a consequence of which a multiple pregnancy would occur.

Currently, artificial insemination occupies an important place in the treatment of single women, but using artificial insemination in other cases, such as in women over 35-36 years old, or in women with endometriosis or in couples who have an Infertility of unknown cause is no longer the first line of treatment as they are very expensive treatment but IUI Treatment Cost in Pakistan give many discounts and also  have 96.2% success rate.