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Are CSL Plasma Donations Taxable? Understanding the Tax Implications
Yes—payments from CSL Plasma for your donations are considered taxable income, not charitable contributions.
IRS Rules & How to Report
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The IRS treats compensation from plasma donation as ordinary taxable income—even if you don’t receive a Form 1099-MISC—for example, if it’s below the $600 reporting threshold.
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This income is reported on Schedule 1 (Form 1040) under “Other income,” regardless of whether a 1099 form was issued.
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If you donate plasma frequently, the IRS considers it a business activity, meaning compensation is taxable as self-employment income—subject to both income and self-employment taxes.
Can You Deduct Related Expenses?
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Yes—since the activity may be treated as business or self-employment, you can deduct ordinary and necessary expenses like mileage, parking, or other costs directly related to donating. Report these on Schedule C and account for self-employment taxes on Schedule SE.
Why Plasma Donations Aren’t Charitable Contributions
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Unlike volunteering or donating property, receiving compensation disqualifies plasma donation from being a tax-deductible charitable act—it’s income, not charity.
In summary:
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CSL plasma compensation is taxable income and must be reported—Form 1099-MISC may or may not be issued.
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If conducted regularly, it's self-employment income—deductible expenses are allowed.
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It’s not a charitable contribution.

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